Interações medicamentosas
Frovatriptan + Methylergonovine
Gravidade: Contraindicada
Frovatriptan and Methylergonovine: contraindicated interaction.
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Resumo
Methylergonovine is an ergot alkaloid with strong vasoconstrictor activity, and combining it with a triptan can cause prolonged vasospasm. This can lead to ischemia and hypertension.
O que esta interação significa em palavras simples
Frovatriptan and Methylergonovine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Additive vasoconstriction from ergot alkaloid and 5-HT1B/1D agonist effects.
O que fazer
Do not use within 24 hours of each other. Use alternative uterotonic or migraine therapy.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Frovatriptan
- Almotriptan + Frovatriptan Contraindicada
- Dihydroergotamine intranasal + Frovatriptan Contraindicada
- Dihydroergotamine + Frovatriptan Contraindicada
- Eletriptan + Frovatriptan Contraindicada
- Ergoloid mesylates + Frovatriptan Contraindicada
- Ergotamine + Frovatriptan Contraindicada
Perguntas frequentes
Can I take Frovatriptan with Methylergonovine?
MediHelp rates the interaction as contraindicated. Frovatriptan and Methylergonovine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methylergonovine is an ergot alkaloid with strong vasoconstrictor activity, and combining it with a triptan can cause prolonged vasospasm. This can lead to ischemia and hypertension.
How serious is the interaction between Frovatriptan and Methylergonovine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use within 24 hours of each other. Use alternative uterotonic or migraine therapy.
What other medicines interact with Frovatriptan?
MediHelp also lists interactions of Frovatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Frovatriptan page.
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