Interações medicamentosas
Olsalazine + Warfarin
Gravidade: Leve
Olsalazine and Warfarin: minor interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Olsalazine is a salicylate-derived aminosalicylate, and salicylates have been reported to potentiate warfarin in isolated cases. Systemic exposure to the active mesalamine is low, so the effect is likely modest.
O que esta interação significa em palavras simples
Olsalazine and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Olsalazine belongs to Gastrointestinal Tract; Warfarin belongs to Cardiovascular.
Por que acontece
Possible small additive effect of salicylate on coagulation; mechanism not firmly established.
O que fazer
Check INR after starting or stopping olsalazine and adjust warfarin if the INR changes.
O que perguntar ao farmacêutico
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Outras interações de Warfarin
- Defibrotide + Warfarin Contraindicada
- Ketorolac + Warfarin Contraindicada
- Abciximab + Warfarin Grave
- Acetylsalicylic acid + Warfarin Grave
- Adagrasib + Warfarin Grave
- Amiodarone + Warfarin Grave
Perguntas frequentes
Can I take Olsalazine with Warfarin?
MediHelp rates the interaction as minor. Olsalazine and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Olsalazine is a salicylate-derived aminosalicylate, and salicylates have been reported to potentiate warfarin in isolated cases. Systemic exposure to the active mesalamine is low, so the effect is likely modest.
How serious is the interaction between Olsalazine and Warfarin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR after starting or stopping olsalazine and adjust warfarin if the INR changes.
What other medicines interact with Warfarin?
MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.
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