Лекарственные взаимодействия
Anti-thymocyte + Etrasimod
Тяжесть: Тяжёлое
Anti-thymocyte and Etrasimod: major interaction.
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Кратко
Etrasimod reduces circulating lymphocytes, and anti-thymocyte globulin profoundly depletes T cells. Used together they may cause additive immunosuppression and a higher risk of serious infection. Combined use has not been studied.
Что означает это взаимодействие простыми словами
Anti-thymocyte and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anti-thymocyte belongs to Miscellaneous; Etrasimod belongs to Gastrointestinal Tract.
Почему это происходит
Additive pharmacodynamic immunosuppression through lymphocyte sequestration (etrasimod) and T-cell depletion (anti-thymocyte globulin).
Что делать
Avoid combining the two where possible, and allow a sufficient interval after anti-thymocyte globulin before starting etrasimod. If given together, monitor closely for infection and check lymphocyte counts.
О чём спросить фармацевта
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Другие взаимодействия Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Противопоказано
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Противопоказано
- Anti-thymocyte + Measles mumps and rubella vaccine live Противопоказано
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Противопоказано
- Anti-thymocyte + Measles vaccine Противопоказано
- Anti-thymocyte + Rotavirus oral vaccine live Противопоказано
Другие взаимодействия Etrasimod
- Abatacept + Etrasimod Тяжёлое
- Amiodarone + Etrasimod Тяжёлое
- Anagrelide + Etrasimod Тяжёлое
- Anakinra + Etrasimod Тяжёлое
- Asenapine + Etrasimod Тяжёлое
- Baricitinib + Etrasimod Тяжёлое
Частые вопросы
Can I take Anti-thymocyte with Etrasimod?
MediHelp rates the interaction as major. Anti-thymocyte and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Etrasimod reduces circulating lymphocytes, and anti-thymocyte globulin profoundly depletes T cells. Used together they may cause additive immunosuppression and a higher risk of serious infection. Combined use has not been studied.
How serious is the interaction between Anti-thymocyte and Etrasimod?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining the two where possible, and allow a sufficient interval after anti-thymocyte globulin before starting etrasimod. If given together, monitor closely for infection and check lymphocyte counts.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.