Лекарственные взаимодействия
Ifosfamide + Measles mumps and rubella vaccine
Тяжесть: Противопоказано
Ifosfamide and Measles mumps and rubella vaccine: contraindicated interaction.
Последнее обновление
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Кратко
Ifosfamide is a cytotoxic alkylating agent that depletes lymphocytes and neutrophils, so live attenuated measles, mumps, rubella and varicella vaccine viruses may replicate without control. This can lead to disseminated vaccine-strain disease and the vaccine also gives poor protection.
Что означает это взаимодействие простыми словами
Ifosfamide and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ifosfamide belongs to Oncology; Measles mumps and rubella vaccine belongs to Miscellaneous.
Почему это происходит
Immunosuppression permits replication of live attenuated vaccine viruses: myelosuppression and lymphocyte depletion
Что делать
Do not give live vaccines during chemotherapy; vaccinate at least 4 weeks before starting and defer until immune recovery (usually at least 3 months after treatment ends).
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Другие взаимодействия Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Противопоказано
- Anakinra + Measles mumps and rubella vaccine Противопоказано
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Противопоказано
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Противопоказано
- Azathioprine + Measles mumps and rubella vaccine Противопоказано
- Basiliximab + Measles mumps and rubella vaccine Противопоказано
Другие взаимодействия Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Противопоказано
- Ifosfamide + Measles mumps and rubella vaccine live Противопоказано
- Ifosfamide + Measles mumps rubella and varicella vaccine live Противопоказано
- Ifosfamide + Measles vaccine Противопоказано
- Ifosfamide + Rotavirus oral vaccine live Противопоказано
- Ifosfamide + Rubella vaccine Противопоказано
Частые вопросы
Can I take Ifosfamide with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Ifosfamide and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ifosfamide is a cytotoxic alkylating agent that depletes lymphocytes and neutrophils, so live attenuated measles, mumps, rubella and varicella vaccine viruses may replicate without control. This can lead to disseminated vaccine-strain disease and the vaccine also gives poor protection.
How serious is the interaction between Ifosfamide and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy; vaccinate at least 4 weeks before starting and defer until immune recovery (usually at least 3 months after treatment ends).
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
