Лекарственные взаимодействия
Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil
Тяжесть: Противопоказано
Influenza virus vaccine quadrivalent intranasal and Mycophenolate mofetil: contraindicated interaction.
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Кратко
The intranasal influenza vaccine contains live attenuated virus, which can replicate in patients taking mycophenolate and cause vaccine-strain disease. Its efficacy may also be reduced. It is contraindicated in significantly immunosuppressed patients.
Что означает это взаимодействие простыми словами
Influenza virus vaccine quadrivalent intranasal and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Почему это происходит
Impaired cellular and humoral immunity from mycophenolate permits uncontrolled replication of live attenuated virus.
Что делать
Do not use the live intranasal vaccine; give an inactivated injectable influenza vaccine instead.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Другие взаимодействия Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Противопоказано
- Bcg vaccine live + Mycophenolate mofetil Противопоказано
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Противопоказано
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Противопоказано
- Measles vaccine + Mycophenolate mofetil Противопоказано
- Mycophenolate mofetil + Rotavirus oral vaccine live Противопоказано
Частые вопросы
Can I take Influenza virus vaccine quadrivalent intranasal with Mycophenolate mofetil?
MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which can replicate in patients taking mycophenolate and cause vaccine-strain disease. Its efficacy may also be reduced. It is contraindicated in significantly immunosuppressed patients.
How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Mycophenolate mofetil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use the live intranasal vaccine; give an inactivated injectable influenza vaccine instead.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Measles mumps and rubella vaccine live. The full list is on the Mycophenolate mofetil page.
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