Лекарственные взаимодействия
Measles vaccine + Prednisone
Тяжесть: Противопоказано
Measles vaccine and Prednisone: contraindicated interaction.
Последнее обновление
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Кратко
Measles vaccine is live attenuated, and immunosuppressive doses of prednisone may allow uncontrolled vaccine virus replication and also reduce the immune response. Live vaccination is generally avoided during high-dose steroid therapy.
Что означает это взаимодействие простыми словами
Measles vaccine and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Почему это происходит
Glucocorticoid immunosuppression impairs control of live attenuated virus replication and reduces vaccine response.
Что делать
Avoid the live measles vaccine during immunosuppressive prednisone therapy and defer it until the steroid has been stopped for the interval in local guidance (typically at least a month). Low-dose or short-course steroids may be acceptable per guidance.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Другие взаимодействия Prednisone
- Bcg vaccine live + Prednisone Противопоказано
- Mifepristone + Prednisone Противопоказано
- Prednisone + Radium-223 dichloride Противопоказано
- Prednisone + Smallpox vaccine live Противопоказано
- Adenovirus types 4 and 7 live + Prednisone Тяжёлое
- Aldesleukin + Prednisone Тяжёлое
Частые вопросы
Can I take Measles vaccine with Prednisone?
MediHelp rates the interaction as contraindicated. Measles vaccine and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated, and immunosuppressive doses of prednisone may allow uncontrolled vaccine virus replication and also reduce the immune response. Live vaccination is generally avoided during high-dose steroid therapy.
How serious is the interaction between Measles vaccine and Prednisone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live measles vaccine during immunosuppressive prednisone therapy and defer it until the steroid has been stopped for the interval in local guidance (typically at least a month). Low-dose or short-course steroids may be acceptable per guidance.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Mifepristone, Radium-223 dichloride. The full list is on the Prednisone page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
