دوا کے تعاملات
Amikacin + Ceftazidime
شدت: معتدل
Amikacin and Ceftazidime: moderate interaction.
آخری تازہ کاری ماخذ: US FDA label
صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔
اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔
خلاصہ
Amikacin is nephrotoxic, and ceftazidime has been reported to add to renal injury when given with aminoglycosides. Cephalosporins alone are rarely nephrotoxic, so the additive risk is modest and mainly relevant with high aminoglycoside exposure, prolonged courses or existing renal impairment. The combination is commonly used deliberately for serious Gram-negative infections.
اس تعامل کا آسان لفظوں میں مطلب
Amikacin and Ceftazidime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amikacin belongs to Anti Bacterial; Ceftazidime belongs to Anti Bacterial.
ایسا کیوں ہوتا ہے
Aminoglycosides accumulate in proximal tubular cells and cause tubular injury; cephalosporins may contribute additional tubular stress, though the mechanism is not clearly established.
کیا کرنا ہے
Use the combination when clinically indicated and dose both drugs for renal function. Monitor serum creatinine and urine output at baseline and at least two to three times weekly, and use amikacin therapeutic drug monitoring to keep troughs low.
فارماسسٹ سے کیا پوچھیں
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ اراکین کے لیے
پورا صفحہ کھولیں
Amikacin اور Ceftazidime کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
ویب پر 7 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔
حوالہ جات
Amikacin کے دیگر تعاملات
- Amikacin + Cidofovir مانع استعمال
- Adefovir + Amikacin شدید
- Amikacin + Amphotericin b شدید
- Amikacin + Amphotericin b deoxycholate شدید
- Amikacin + Atracurium شدید
- Amikacin + Bacitracin شدید
Ceftazidime کے دیگر تعاملات
اکثر پوچھے جانے والے سوالات
Can I take Amikacin with Ceftazidime?
MediHelp rates the interaction as moderate. Amikacin and Ceftazidime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amikacin is nephrotoxic, and ceftazidime has been reported to add to renal injury when given with aminoglycosides. Cephalosporins alone are rarely nephrotoxic, so the additive risk is modest and mainly relevant with high aminoglycoside exposure, prolonged courses or existing renal impairment. The combination is commonly used deliberately for serious Gram-negative infections.
How serious is the interaction between Amikacin and Ceftazidime?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the combination when clinically indicated and dose both drugs for renal function. Monitor serum creatinine and urine output at baseline and at least two to three times weekly, and use amikacin therapeutic drug monitoring to keep troughs low.
What other medicines interact with Amikacin?
MediHelp also lists interactions of Amikacin with, for example, Cidofovir, Adefovir, Amphotericin b. The full list is on the Amikacin page.
MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر
MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔
