دوا کے تعاملات
Bupropion + Phenelzine
شدت: مانع استعمال
Bupropion and Phenelzine: contraindicated interaction.
آخری تازہ کاری ماخذ: US FDA label
صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔
اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔
خلاصہ
Bupropion is contraindicated with MAO inhibitors because of the risk of hypertensive reactions and neurotoxicity. Labeling requires at least 14 days between stopping an MAOI such as phenelzine and starting bupropion. Seizure risk may also be raised.
اس تعامل کا آسان لفظوں میں مطلب
Bupropion and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Bupropion belongs to Central Nervous System; Phenelzine belongs to Central Nervous System.
ایسا کیوں ہوتا ہے
Bupropion inhibits noradrenaline and dopamine reuptake while MAO inhibition increases catecholamine stores, producing excessive adrenergic stimulation; bupropion also lowers seizure threshold.
کیا کرنا ہے
Do not combine; wait at least 14 days after stopping phenelzine before starting bupropion, and at least 14 days after bupropion before starting phenelzine is a conservative approach. Use a different smoking cessation or antidepressant strategy during MAOI treatment.
فارماسسٹ سے کیا پوچھیں
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ اراکین کے لیے
پورا صفحہ کھولیں
Bupropion اور Phenelzine کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
ویب پر 14 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔
حوالہ جات
Bupropion کے دیگر تعاملات
- Bupropion + Isocarboxazid مانع استعمال
- Bupropion + Linezolid مانع استعمال
- Bupropion + Rasagiline مانع استعمال
- Bupropion + Selegiline مانع استعمال
- Bupropion + Selegiline transdermal مانع استعمال
- Bupropion + Thioridazine مانع استعمال
Phenelzine کے دیگر تعاملات
- 5-HTP + Phenelzine مانع استعمال
- Amitriptyline + Phenelzine مانع استعمال
- Amoxapine + Phenelzine مانع استعمال
- Atomoxetine + Phenelzine مانع استعمال
- Benzphetamine + Phenelzine مانع استعمال
- Brimonidine + Phenelzine مانع استعمال
اکثر پوچھے جانے والے سوالات
Can I take Bupropion with Phenelzine?
MediHelp rates the interaction as contraindicated. Bupropion and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Bupropion is contraindicated with MAO inhibitors because of the risk of hypertensive reactions and neurotoxicity. Labeling requires at least 14 days between stopping an MAOI such as phenelzine and starting bupropion. Seizure risk may also be raised.
How serious is the interaction between Bupropion and Phenelzine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; wait at least 14 days after stopping phenelzine before starting bupropion, and at least 14 days after bupropion before starting phenelzine is a conservative approach. Use a different smoking cessation or antidepressant strategy during MAOI treatment.
What other medicines interact with Bupropion?
MediHelp also lists interactions of Bupropion with, for example, Isocarboxazid, Linezolid, Rasagiline. The full list is on the Bupropion page.
MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر
MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔
