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Ciprofloxacin + Theophylline

شدت: شدید

Ciprofloxacin and Theophylline: major interaction.

آخری تازہ کاری ماخذ: US FDA label

صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔

اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔

خلاصہ

Ciprofloxacin reduces theophylline clearance and can raise serum theophylline concentrations substantially in some patients. This can lead to nausea, tachycardia, arrhythmias and seizures. Elderly patients, those with high baseline levels, liver disease or heart failure, and smokers who stop are at greater risk.

اس تعامل کا آسان لفظوں میں مطلب

Ciprofloxacin and Theophylline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Ciprofloxacin belongs to Anti Bacterial; Theophylline belongs to Respiratory.

شواہد کی سطح: High

ایسا کیوں ہوتا ہے

Ciprofloxacin inhibits CYP1A2, the main enzyme metabolising theophylline, decreasing its clearance.

کیا کرنا ہے

Prefer an antibiotic that does not inhibit CYP1A2. If ciprofloxacin is needed, measure theophylline levels before and during therapy and reduce the theophylline dose empirically.

فارماسسٹ سے کیا پوچھیں

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ اراکین کے لیے

پورا صفحہ کھولیں

Ciprofloxacin اور Theophylline کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

ویب پر 14 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔

حوالہ جات

اکثر پوچھے جانے والے سوالات

Can I take Ciprofloxacin with Theophylline?

MediHelp rates the interaction as major. Ciprofloxacin and Theophylline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ciprofloxacin reduces theophylline clearance and can raise serum theophylline concentrations substantially in some patients. This can lead to nausea, tachycardia, arrhythmias and seizures. Elderly patients, those with high baseline levels, liver disease or heart failure, and smokers who stop are at greater risk.

How serious is the interaction between Ciprofloxacin and Theophylline?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer an antibiotic that does not inhibit CYP1A2. If ciprofloxacin is needed, measure theophylline levels before and during therapy and reduce the theophylline dose empirically.

What other medicines interact with Theophylline?

MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.

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