Drug interactions
ciprofloxacin + theophylline
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↑ theophylline → seizures/arrhythmias.
Mechanism of action
CYP1A2 inhibition.
Clinical management
Avoid or reduce dose and monitor levels.
Drug reference
References
Frequently asked questions
Can I take ciprofloxacin with theophylline?
The interaction is rated: Major. ↑ theophylline → seizures/arrhythmias.
How serious is the interaction between ciprofloxacin and theophylline?
The interaction is rated: Major. Evidence level: High.
How is the interaction between ciprofloxacin and theophylline managed?
Avoid or reduce dose and monitor levels.
Why do ciprofloxacin and theophylline interact?
CYP1A2 inhibition.
Full monographs, dosing and an interaction checker in the MediHelp app
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