دوا کے تعاملات
Etoricoxib + Venlafaxine
شدت: معتدل
Etoricoxib and Venlafaxine: moderate interaction.
آخری تازہ کاری ماخذ: US FDA label
صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔
اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔
خلاصہ
Venlafaxine and NSAIDs including selective COX-2 inhibitors such as etoricoxib each increase the risk of bleeding, and together the risk of gastrointestinal and other haemorrhage is higher. The absolute risk is modest in healthy patients but meaningful in older adults and those with prior ulcers. Etoricoxib may carry less gastric toxicity than non-selective NSAIDs but does not remove this risk.
اس تعامل کا آسان لفظوں میں مطلب
Etoricoxib and Venlafaxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Etoricoxib belongs to Musculoskeletal; Venlafaxine belongs to Central Nervous System.
ایسا کیوں ہوتا ہے
Venlafaxine inhibits serotonin reuptake into platelets, depleting platelet serotonin and impairing aggregation, while NSAIDs add mucosal injury and effects on haemostasis. Etoricoxib may also raise blood pressure, which venlafaxine can also do.
کیا کرنا ہے
Use the lowest effective etoricoxib dose for the shortest duration, and consider a PPI in patients with risk factors for GI bleeding. Monitor for bruising, melaena, haematemesis and check blood count if use is prolonged.
فارماسسٹ سے کیا پوچھیں
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ اراکین کے لیے
پورا صفحہ کھولیں
Etoricoxib اور Venlafaxine کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
ویب پر 7 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔
حوالہ جات
- Effexor XR (venlafaxine) Prescribing Information - Warnings and Precautions: Abnormal Bleeding — FDA Label
- Arcoxia (etoricoxib) Summary of Product Characteristics — EMA SmPC
Venlafaxine کے دیگر تعاملات
- Isocarboxazid + Venlafaxine مانع استعمال
- Methylene blue + Venlafaxine مانع استعمال
- Phenelzine + Venlafaxine مانع استعمال
- Procarbazine + Venlafaxine مانع استعمال
- Rasagiline + Venlafaxine مانع استعمال
- Safinamide + Venlafaxine مانع استعمال
اکثر پوچھے جانے والے سوالات
Can I take Etoricoxib with Venlafaxine?
MediHelp rates the interaction as moderate. Etoricoxib and Venlafaxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Venlafaxine and NSAIDs including selective COX-2 inhibitors such as etoricoxib each increase the risk of bleeding, and together the risk of gastrointestinal and other haemorrhage is higher. The absolute risk is modest in healthy patients but meaningful in older adults and those with prior ulcers. Etoricoxib may carry less gastric toxicity than non-selective NSAIDs but does not remove this risk.
How serious is the interaction between Etoricoxib and Venlafaxine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective etoricoxib dose for the shortest duration, and consider a PPI in patients with risk factors for GI bleeding. Monitor for bruising, melaena, haematemesis and check blood count if use is prolonged.
What other medicines interact with Venlafaxine?
MediHelp also lists interactions of Venlafaxine with, for example, Isocarboxazid, Methylene blue, Phenelzine. The full list is on the Venlafaxine page.
MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر
MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔
