Diseases
cholangitis
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Cholangitis is an inflammation of the bile duct system. The bile duct system carries bile from your liver and gallbladder into the first part of your small intestine (the duodenum). In most cases cholangitis is caused by a bacterial infection, and often happens suddenly. But in some cases it may be long-term (chronic).
Symptoms
- fatigue
- itchy skin
- dry eyes and mouth
- swelling of the spleen (splenomegaly)
Causes
- it's not clear what causes primary biliary cholangitis. many experts consider it an autoimmune disease in which the body turns against its own cells
Risk factors
- sex. most people with primary biliary cholangitis are women.
- age. it's most likely to occur in people 30 to 60 years old.
Diagnosis
- medical history
- liver tests.
- antibody tests for signs of autoimmune disease.
- cholesterol test.
Medicines used
Frequently asked questions
What is cholangitis?
Cholangitis is an inflammation of the bile duct system. The bile duct system carries bile from your liver and gallbladder into the first part of your small intestine (the duodenum). In most cases cholangitis is caused by a bacterial infection, and often happens suddenly. But in some cases it may be long-term (chronic).
What are the symptoms of cholangitis?
fatigue, itchy skin, dry eyes and mouth, swelling of the spleen (splenomegaly)
What causes cholangitis?
it's not clear what causes primary biliary cholangitis. many experts consider it an autoimmune disease in which the body turns against its own cells
Which medicines are used for cholangitis?
obeticholic acid, piperacillin
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