Diseases
graft versus host disease
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Graft vs. host disease is a rare disease, It happens as a complication of bone marrow transplantation, which is equivalent to stem cell transplantation. What happens is that the immune cells of the donor, they recognize your body as the foreign tissue or foreign organ, and they reject your body.
Symptoms
- skin rash
- yellow discoloration of the skin and/or eyes
- dry mouth
- nausea, vomiting, diarrhea, or abdominal cramping
- fatigue, muscle weakness, or pain
Causes
- body rejecting the new organ
Risk factors
- difference in human leukocyte antigen
- the advanced age of either the donor or the recipient.
Diagnosis
- physical exam
- diagnosis by exclusion of other causes.
Medicines used
Frequently asked questions
What is graft versus host disease?
Graft vs. host disease is a rare disease, It happens as a complication of bone marrow transplantation, which is equivalent to stem cell transplantation. What happens is that the immune cells of the donor, they recognize your body as the foreign tissue or foreign organ, and they reject your body.
What are the symptoms of graft versus host disease?
skin rash, yellow discoloration of the skin and/or eyes, dry mouth, nausea, vomiting, diarrhea, or abdominal cramping, fatigue, muscle weakness, or pain
What causes graft versus host disease?
body rejecting the new organ
Which medicines are used for graft versus host disease?
abatacept, basiliximab, ruxolitinib
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