Drug reference
abatacept
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (TNF-alpha Inhibitors)
Mechanism of action
Abatacept, a selective costimulation modulator, inhibits T cell (T lymphocyte) activation by binding to CD80 and CD86, thereby blocking interaction with CD28. This interaction provides a costimulatory signal necessary for full activation of T lymphocytes.
Common side effects
- Nasopharyngitis
- Dizziness
- Headache
- Nausea
- Infection
- Cough
Contraindications
- None listed by the manufacturer
Known interactions (6)
- abatacept + adalimumab Major
- abatacept + anakinra Major
- abatacept + etanercept Major
- abatacept + infliximab Major
- abatacept + tocilizumab Major
- abatacept + upadacitinib Major
Related conditions
Frequently asked questions
What drug class is abatacept?
abatacept belongs to: Musculoskeletal.
How does abatacept work?
Abatacept, a selective costimulation modulator, inhibits T cell (T lymphocyte) activation by binding to CD80 and CD86, thereby blocking interaction with CD28. This interaction provides a costimulatory signal necessary for full activation of T lymphocytes.
What are the common side effects of abatacept?
Nasopharyngitis, Dizziness, Headache, Nausea, Infection, Cough
Which drugs interact with abatacept?
adalimumab, anakinra, etanercept, infliximab, tocilizumab, upadacitinib
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