Diseases
nephrogenic diabetes insipidus
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Nephrogenic diabetes insipidus. Nephrogenic diabetes insipidus occurs when there's a defect in the structures in your kidneys that makes the kidneys unable to properly respond to ADH. The defect may be due to an inherited (genetic) disorder or a chronic kidney disorder.
Symptoms
- being extremely thirsty
- producing large amounts of pale urine
- frequently needing to get up to urinate during the night
- preferring cold drinks
Causes
- certain drugs, such as lithium or antiviral medications such as foscarnet (foscavir), also can cause nephrogenic diabetes insipidus.
Risk factors
- nephrogenic diabetes insipidus that's present at or shortly after birth usually
- ... has an inherited (genetic) cause that permanently changes the kidneys' ...
- ... ability to concentrate urine.
Diagnosis
- magnetic resonance imaging (mri)
- water deprivation test.
- urinalysis
- genetic screening
Medicines used
Frequently asked questions
What is nephrogenic diabetes insipidus?
Nephrogenic diabetes insipidus. Nephrogenic diabetes insipidus occurs when there's a defect in the structures in your kidneys that makes the kidneys unable to properly respond to ADH. The defect may be due to an inherited (genetic) disorder or a chronic kidney disorder.
What are the symptoms of nephrogenic diabetes insipidus?
being extremely thirsty, producing large amounts of pale urine, frequently needing to get up to urinate during the night, preferring cold drinks
What causes nephrogenic diabetes insipidus?
certain drugs, such as lithium or antiviral medications such as foscarnet (foscavir), also can cause nephrogenic diabetes insipidus.
Which medicines are used for nephrogenic diabetes insipidus?
indomethacin
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.