Diseases
osteolytic bone lesions of MM
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Also known as bone lesions or osteolytic lesions, lytic lesions are spots of bone damage that result from cancerous plasma cells building up in your bone marrow.
Symptoms
- pain
- fractures
- hypercalcemia
- limping
- low blood cell counts.
Causes
- with myeloma, the cancerous plasma cells (called myeloma cells) make chemicals called osteoclast activating factors (oafs). these oafs tell the osteoclasts to break down bone faster than usual, so old bone is broken ...
- down bone faster than usual, so old bone is broken down faster than new bone is made.
Risk factors
- multiple myeloma
Diagnosis
- bone marrow biopsy.
- bone marrow aspiration.
Medicines used
Frequently asked questions
What is osteolytic bone lesions of MM?
Also known as bone lesions or osteolytic lesions, lytic lesions are spots of bone damage that result from cancerous plasma cells building up in your bone marrow.
What are the symptoms of osteolytic bone lesions of MM?
pain, fractures, hypercalcemia, limping, low blood cell counts.
What causes osteolytic bone lesions of MM?
with myeloma, the cancerous plasma cells (called myeloma cells) make chemicals called osteoclast activating factors (oafs). these oafs tell the osteoclasts to break down bone faster than usual, so old bone is broken ...; down bone faster than usual, so old bone is broken down faster than new bone is made.
Which medicines are used for osteolytic bone lesions of MM?
clodronate, pamidronate
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