Drug reference

clodronate

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Musculoskeletal (Bisphosphonate)

Mechanism of action

Bisphosphonate; binds to hydroxyapatite crystals in bone and inhibits osteoclast-mediated bone resorption; decreases mineral release and collagen or matrix breakdown in bone

Common side effects

  • Bronchospasm
  • Vomiting
  • Nausea
  • Hypocalcaemia
  • Increased AST
  • Diarrhea

Related conditions

Frequently asked questions

What drug class is clodronate?

clodronate belongs to: Musculoskeletal.

How does clodronate work?

Bisphosphonate; binds to hydroxyapatite crystals in bone and inhibits osteoclast-mediated bone resorption; decreases mineral release and collagen or matrix breakdown in bone

What are the common side effects of clodronate?

Bronchospasm, Vomiting, Nausea, Hypocalcaemia, Increased AST, Diarrhea

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