Diseases
osteolytic bone metastases of BC
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
The most common skeletal complication of breast cancer is osteolytic bone metastasis. Bone metastases are present in 80% of patients with advanced disease and cause significant morbidity. They are most often osteolytic, but can be osteoblastic or mixed.
Symptoms
- bone pain.
- broken bones.
- bowel incontinence.
- weakness in the legs or arms.
- high levels of calcium in the blood (hypercalcemia)
Causes
- cancer merastases
Risk factors
- age
- menopausal status
- number of axillary lymph node metastases, and tumor size
Diagnosis
- blood tests.
- imaging tests.
Medicines used
Frequently asked questions
What is osteolytic bone metastases of BC?
The most common skeletal complication of breast cancer is osteolytic bone metastasis. Bone metastases are present in 80% of patients with advanced disease and cause significant morbidity. They are most often osteolytic, but can be osteoblastic or mixed.
What are the symptoms of osteolytic bone metastases of BC?
bone pain., broken bones., bowel incontinence., weakness in the legs or arms., high levels of calcium in the blood (hypercalcemia)
What causes osteolytic bone metastases of BC?
cancer merastases
Which medicines are used for osteolytic bone metastases of BC?
clodronate, pamidronate
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