Diseases
von willebrand disease (type 1)
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
This is the most common and mildest form of VWD, in which a person has lower-than-normal levels of VWF. A person with Type 1 VWD also might have low levels of factor VIII (8), another type of blood-clotting protein. About 85% of people treated for VWD have Type 1.
Symptoms
- excessive bleeding from an injury or after surgery or dental work
- frequent nosebleeds that don't stop within 10 minutes
- heavy or long menstrual bleeding
- blood in your urine or stool
- heavy bleeding during labor and delivery
Causes
- the usual cause of von willebrand disease is an inherited abnormal gene that controls von willebrand factor — a protein that plays a key role in blood clotting.
Risk factors
- the main risk factor for von willebrand disease is having a family history of it
Diagnosis
- von willebrand factor antigen.
- von willebrand factor activity
- factor viii clotting activity.
- von willebrand factor multimers.
Medicines used
Frequently asked questions
What is von willebrand disease (type 1)?
This is the most common and mildest form of VWD, in which a person has lower-than-normal levels of VWF. A person with Type 1 VWD also might have low levels of factor VIII (8), another type of blood-clotting protein. About 85% of people treated for VWD have Type 1.
What are the symptoms of von willebrand disease (type 1)?
excessive bleeding from an injury or after surgery or dental work, frequent nosebleeds that don't stop within 10 minutes, heavy or long menstrual bleeding, blood in your urine or stool, heavy bleeding during labor and delivery
What causes von willebrand disease (type 1)?
the usual cause of von willebrand disease is an inherited abnormal gene that controls von willebrand factor — a protein that plays a key role in blood clotting.
Which medicines are used for von willebrand disease (type 1)?
desmopressin
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