Diseases
zollinger-ellison syndrome
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Zollinger-Ellison syndrome is a rare condition in which one or more tumors form in your pancreas or the upper part of your small intestine (duodenum). These tumors, called gastrinomas, secrete large amounts of the hormone gastrin, which causes your stomach to produce too much acid.
Symptoms
- abdominal pain
- burning, aching, gnawing or discomfort in your upper abdomen
- acid reflux and heartburn
- unintended weight loss
- decreased appetite
Causes
- the exact cause of zollinger-ellison syndrome remains unknown. but the sequence of events that occurs in zollinger-ellison syndrome is clear.
Risk factors
- if you have a blood relative, such as a sibling or parent, with the disease...
- it's more likely that you'll have zollinger-ellison syndrome.
Diagnosis
- blood tests.
- medical history.
- upper gastrointestinal endoscopy.
- endoscopic ultrasound.
Medicines used
Frequently asked questions
What is zollinger-ellison syndrome?
Zollinger-Ellison syndrome is a rare condition in which one or more tumors form in your pancreas or the upper part of your small intestine (duodenum). These tumors, called gastrinomas, secrete large amounts of the hormone gastrin, which causes your stomach to produce too much acid.
What are the symptoms of zollinger-ellison syndrome?
abdominal pain, burning, aching, gnawing or discomfort in your upper abdomen, acid reflux and heartburn, unintended weight loss, decreased appetite
What causes zollinger-ellison syndrome?
the exact cause of zollinger-ellison syndrome remains unknown. but the sequence of events that occurs in zollinger-ellison syndrome is clear.
Which medicines are used for zollinger-ellison syndrome?
cimetidine, esomeprazole, famotidine, lansoprazole, omeprazole, pantoprazole, rabeprazole, ranitidine
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