Drug reference
alfuzosin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Genitourinary (Alpha-1 Blockers)
Mechanism of action
Selective antagonist of postsynaptic alpha-1-adrenoceptors; blockade of adrenoreceptors in the prostate, prostatic capsule, bladder neck and prostatic urethra.
Common side effects
- Dizziness
- Headache
- Back pain
- Brochitis
- Abdominal pain
Contraindications
- Hypersensitivity Moderate to severe liver impairment Coadministration with potent CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir) or other alpha1-blocking agents
Known interactions (14)
- alfuzosin + itraconazole Contraindicated
- alfuzosin + ketoconazole Contraindicated
- alfuzosin + cisapride Major
- alfuzosin + clarithromycin Major
- alfuzosin + dronedarone Major
- alfuzosin + mifepristone Major
- alfuzosin + pimozide Major
- alfuzosin + ribociclib Major
- alfuzosin + thioridazine Major
- alfuzosin + chloramphenicol Moderate
- alfuzosin + fluconazole Moderate
- alfuzosin + posaconazole Moderate
- alfuzosin + vardenafil Moderate
- alfuzosin + voriconazole Moderate
Related conditions
Frequently asked questions
What drug class is alfuzosin?
alfuzosin belongs to: Genitourinary.
How does alfuzosin work?
Selective antagonist of postsynaptic alpha-1-adrenoceptors; blockade of adrenoreceptors in the prostate, prostatic capsule, bladder neck and prostatic urethra.
What are the common side effects of alfuzosin?
Dizziness, Headache, Back pain, Brochitis, Abdominal pain
Which drugs interact with alfuzosin?
itraconazole, ketoconazole, cisapride, clarithromycin, dronedarone, mifepristone, pimozide, ribociclib, thioridazine, chloramphenicol, fluconazole, posaconazole, vardenafil, voriconazole
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