Drug reference
alprostadil
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Genitourinary (Prostaglandin Analogues)
Mechanism of action
Relaxes arterial smooth muscle, producing vasodilation; allows blood flow and entrapment in the lacunar spaces of the penis.
Common side effects
- Penile pain
- Headache
- Urethral burning
- Urethral bleeding/spotting
- Testicular pain
Contraindications
- Hypersensitivity Predisposition to priapism (eg, sickle cell anemia, sickle cell trait, multiple myeloma, leukemia) Anatomical deformation of the penis, such as cavernosal fibrosis or Peyronie’s disease Penile implants Sexual intercourse with pregnant woman unless condom barrier used (i…
Related conditions
Frequently asked questions
What drug class is alprostadil?
alprostadil belongs to: Genitourinary.
How does alprostadil work?
Relaxes arterial smooth muscle, producing vasodilation; allows blood flow and entrapment in the lacunar spaces of the penis.
What are the common side effects of alprostadil?
Penile pain, Headache, Urethral burning, Urethral bleeding/spotting, Testicular pain
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