Drug reference
ampicillin-sulbactam
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Penicillins)
Mechanism of action
Drug combination of beta-lactamase inhibitor with ampicillin; interferes with bacterial cell wall synthesis during active replication, causing bactericidal activity against susceptible organisms; alternative to amoxicillin when unable to take medication orally; covers skin, enteric flora, and anaerobes; not ideal for nosocomial pathogens.
Common side effects
- IM injection site pain
- IV injection site pain
- Thrombophlebitis
- Diarrhea
Contraindications
- Hypersensitivity to drug or components Patients with previous history of cholestatic jaundice/hepatic dysfunction associated with ampicillin sulbactam
Related conditions
Frequently asked questions
What drug class is ampicillin-sulbactam?
ampicillin-sulbactam belongs to: Anti Bacterial.
How does ampicillin-sulbactam work?
Drug combination of beta-lactamase inhibitor with ampicillin; interferes with bacterial cell wall synthesis during active replication, causing bactericidal activity against susceptible organisms; alternative to amoxicillin when unable to take medication orally; covers skin, enteric flora, and anaerobes; not ideal for nosocomial pathogens.
What are the common side effects of ampicillin-sulbactam?
IM injection site pain, IV injection site pain, Thrombophlebitis, Diarrhea
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