Drug reference
buspirone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Miscellaneous(CNS))
Mechanism of action
Is an azaspirodecanedione; high affinity for serotonin 5HT1A and 5HT2 receptors and moderate affinity for dopamine D2 receptors, but no effect on benzodiazepine GABA receptors No anticonvulsant, muscle relaxant, or sedative effects
Common side effects
- Nervousness
- Dizziness
- Drowsiness
- Headache
- Blurred vision
- Nausea
Known interactions (7)
- buspirone + isocarboxazid Contraindicated
- buspirone + linezolid Contraindicated
- buspirone + phenelzine Contraindicated
- buspirone + procarbazine Contraindicated
- buspirone + selegiline Contraindicated
- buspirone + tranylcypromine Contraindicated
- buspirone + escitalopram Moderate
Related conditions
Frequently asked questions
What drug class is buspirone?
buspirone belongs to: Central Nervous System.
How does buspirone work?
Is an azaspirodecanedione; high affinity for serotonin 5HT1A and 5HT2 receptors and moderate affinity for dopamine D2 receptors, but no effect on benzodiazepine GABA receptors No anticonvulsant, muscle relaxant, or sedative effects
What are the common side effects of buspirone?
Nervousness, Dizziness, Drowsiness, Headache, Blurred vision, Nausea
Which drugs interact with buspirone?
isocarboxazid, linezolid, phenelzine, procarbazine, selegiline, tranylcypromine, escitalopram
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