Drug reference
desvenlafaxine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (SNRIs)
Mechanism of action
Potent SNRI; major active metabolite of venlafaxine
Common side effects
- Insomnia
- Dry mouth
- Constipation
- Dizziness
- Somnolence
- Nausea
- Hyperhidrosis
Known interactions (8)
- desvenlafaxine + isocarboxazid Contraindicated
- desvenlafaxine + phenelzine Contraindicated
- desvenlafaxine + rasagiline Contraindicated
- desvenlafaxine + safinamide Contraindicated
- desvenlafaxine + selegiline Contraindicated
- desvenlafaxine + tranylcypromine Contraindicated
- desvenlafaxine + linezolid Major
- desvenlafaxine + procarbazine Major
Related conditions
Frequently asked questions
What drug class is desvenlafaxine?
desvenlafaxine belongs to: Central Nervous System.
How does desvenlafaxine work?
Potent SNRI; major active metabolite of venlafaxine
What are the common side effects of desvenlafaxine?
Insomnia, Dry mouth, Constipation, Dizziness, Somnolence, Nausea, Hyperhidrosis
Which drugs interact with desvenlafaxine?
isocarboxazid, phenelzine, rasagiline, safinamide, selegiline, tranylcypromine, linezolid, procarbazine
Full monographs, dosing and an interaction checker in the MediHelp app
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