Drug reference
doxycycline
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Cyclines)
Mechanism of action
Inhibits protein synthesis and, thus, bacterial growth by binding to 30S and possibly 50S ribosomal subunits of susceptible bacteria; may block dissociation of peptidyl t-RNA from ribosomes, causing RNA-dependent protein synthesis to arrest.
Common side effects
- Anorexia
- Dental discoloration
- Enterocolitis
- Esophageal ulcer
- Diarrhea
Known interactions (7)
- acitretin + doxycycline Contraindicated
- doxycycline + isotretinoin Major
- doxycycline + tretinoin Major
- digoxin + doxycycline Moderate
- doxycycline + flibanserin Moderate
- doxycycline + iron (oral) Moderate
- doxycycline + strontium ranelate Moderate
Related conditions
Frequently asked questions
What drug class is doxycycline?
doxycycline belongs to: Anti Bacterial.
How does doxycycline work?
Inhibits protein synthesis and, thus, bacterial growth by binding to 30S and possibly 50S ribosomal subunits of susceptible bacteria; may block dissociation of peptidyl t-RNA from ribosomes, causing RNA-dependent protein synthesis to arrest.
What are the common side effects of doxycycline?
Anorexia, Dental discoloration, Enterocolitis, Esophageal ulcer, Diarrhea
Which drugs interact with doxycycline?
acitretin, isotretinoin, tretinoin, digoxin, flibanserin, iron (oral), strontium ranelate
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