Drug reference
lactulose
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Gastrointestinal Tract (Osmotic Laxative)
Mechanism of action
Hyperosmotic agent increases stool water contents, softens stool, promotes peristalsis, and reduces blood ammonia concentration. Portal systemic encephalopathy: Breakdown of lactulose to organic acids by colonic bacteria acidifies colonic contents, thereby subsequently inhibiting diffusion of ammonia back to blood.
Common side effects
- Abdominal cramping
- Excessive bowel activity
- Dehydration
- Diarrhea
Contraindications
- Galactosemia (patients require low-galactose diet)
Related conditions
Frequently asked questions
What drug class is lactulose?
lactulose belongs to: Gastrointestinal Tract.
How does lactulose work?
Hyperosmotic agent increases stool water contents, softens stool, promotes peristalsis, and reduces blood ammonia concentration. Portal systemic encephalopathy: Breakdown of lactulose to organic acids by colonic bacteria acidifies colonic contents, thereby subsequently inhibiting diffusion of ammonia back to blood.
What are the common side effects of lactulose?
Abdominal cramping, Excessive bowel activity, Dehydration, Diarrhea
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.