Drug reference
lapatinib
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Oncology (TK Inhibitors)
Mechanism of action
Kinase inhibitor, blocks EGF-receptor HER2 kinase; tyrosing kinase inhibition possibly blocks angiogenesis and cellular proliferation
Common side effects
- Rash
- Anemia
- Vomiting
- Nausea
- Hand-foot synd
- Increased LFTs
- Diarrhea
Known interactions (6)
- dronedarone + lapatinib Major
- ergotamine + lapatinib Major
- erythromycin + lapatinib Major
- flibanserin + lapatinib Major
- colchicine + lapatinib Moderate
- everolimus + lapatinib Moderate
Related conditions
Frequently asked questions
What drug class is lapatinib?
lapatinib belongs to: Oncology.
How does lapatinib work?
Kinase inhibitor, blocks EGF-receptor HER2 kinase; tyrosing kinase inhibition possibly blocks angiogenesis and cellular proliferation
What are the common side effects of lapatinib?
Rash, Anemia, Vomiting, Nausea, Hand-foot synd, Increased LFTs, Diarrhea
Which drugs interact with lapatinib?
dronedarone, ergotamine, erythromycin, flibanserin, colchicine, everolimus
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.