Drug reference
ledipasvir-sofosbuvir
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Virals (Hepatits Viruses)
Mechanism of action
Ledipasvir: Inhibits HCV NS5A protein, which is required for viral replication; Sofosbuvir: Nucleotide prodrug that undergoes metabolism to the active uridine analog triphosphate
Common side effects
- Asthenia
- Headache
- Fatigue
- Nausea
- Cough
- Diarrhea
Contraindications
- If coadministered with ribavirin, the contraindications to ribavirin also apply to this combination regimen
Known interactions (2)
Related conditions
Frequently asked questions
What drug class is ledipasvir-sofosbuvir?
ledipasvir-sofosbuvir belongs to: Anti Virals.
How does ledipasvir-sofosbuvir work?
Ledipasvir: Inhibits HCV NS5A protein, which is required for viral replication; Sofosbuvir: Nucleotide prodrug that undergoes metabolism to the active uridine analog triphosphate
What are the common side effects of ledipasvir-sofosbuvir?
Asthenia, Headache, Fatigue, Nausea, Cough, Diarrhea
Which drugs interact with ledipasvir-sofosbuvir?
carbamazepine, colchicine
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