Drug reference
loteprednol
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Miscellaneous (Eye Preparations)
Mechanism of action
There is no generally accepted explanation for the mechanism of action of ocular corticosteroids However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins It is believed that these proteins control the biosynthesis of potent mediators of inflammation (eg, prostaglandins, leukotrienes) by inhibiting the release of arachid
Common side effects
- Foreign body sensation
- Anterior chamber inflammation
- Abnormal vision/blurring
- Burning on instillation
- Chemosis
- Discharge
Contraindications
- Most viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures
- Hypersensitivity to any component of the formulation
Frequently asked questions
What drug class is loteprednol?
loteprednol belongs to: Miscellaneous.
How does loteprednol work?
There is no generally accepted explanation for the mechanism of action of ocular corticosteroids However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins It is believed that these proteins control the biosynthesis of potent mediators of inflammation (eg, prostaglandins, leukotrienes) by inhibiting the release of arachid
What are the common side effects of loteprednol?
Foreign body sensation, Anterior chamber inflammation, Abnormal vision/blurring, Burning on instillation, Chemosis, Discharge
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