Drug reference
netupitant-palonosetron
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Gastrointestinal Tract (Combination(GIT))
Mechanism of action
Netupitant: Tachykinin NK1 receptor (substance P) antagonist. Palonosetron: 5-hydroxytryptamine 3 (5-HT3) receptor antagonist; binds to 5-HT3 receptors both in peripheral and central nervous system, with primary effects in GI tract.
Common side effects
- Asthenia
- Dyspepsia
- Headache
- Fatigue
Known interactions (1)
- flibanserin + netupitant-palonosetron Contraindicated
Related conditions
Frequently asked questions
What drug class is netupitant-palonosetron?
netupitant-palonosetron belongs to: Gastrointestinal Tract.
How does netupitant-palonosetron work?
Netupitant: Tachykinin NK1 receptor (substance P) antagonist. Palonosetron: 5-hydroxytryptamine 3 (5-HT3) receptor antagonist; binds to 5-HT3 receptors both in peripheral and central nervous system, with primary effects in GI tract.
What are the common side effects of netupitant-palonosetron?
Asthenia, Dyspepsia, Headache, Fatigue
Which drugs interact with netupitant-palonosetron?
flibanserin
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