Drug reference
pirfenidone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Miscellaneous (Miscellaneous)
Mechanism of action
Precise mechanism by which pirfenidone may work in pulmonary fibrosis has not been established Inhibits transforming growth factor (TGF)-beta, a chemical mediator that controls many cell functions including proliferation and differentiation Also inhibits the synthesis of TNF-alpha, a cytokine that is known to have an active role in inflammation
Common side effects
- Abdominal Pain
- Rash
- Headache
- Fatigue
- Nausea
- Diarrhea
Known interactions (1)
Related conditions
Frequently asked questions
What drug class is pirfenidone?
pirfenidone belongs to: Miscellaneous.
How does pirfenidone work?
Precise mechanism by which pirfenidone may work in pulmonary fibrosis has not been established Inhibits transforming growth factor (TGF)-beta, a chemical mediator that controls many cell functions including proliferation and differentiation Also inhibits the synthesis of TNF-alpha, a cytokine that is known to have an active role in inflammation
What are the common side effects of pirfenidone?
Abdominal Pain, Rash, Headache, Fatigue, Nausea, Diarrhea
Which drugs interact with pirfenidone?
carbamazepine
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