Drug reference
regorafenib
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Oncology (Anti Neoplastics)
Mechanism of action
Tyrosine kinase inhibitor; shown to inhibit activity of membrane-bound and intracellular kinases involved in normal cellular functions and in pathological processes (eg, oncogenesis, tumor angiogenesis)
Common side effects
- Asthenia
- Anemia
- Increased AST
- Lymphopenia
- Proteinuria
- Hypocalcemia
- Hypophosphatemia
Known interactions (9)
- carbamazepine + regorafenib Major
- clarithromycin + regorafenib Major
- enzalutamide + regorafenib Major
- bosentan + regorafenib Moderate
- chloramphenicol + regorafenib Moderate
- dexamethasone + regorafenib Moderate
- eslicarbazepine + regorafenib Moderate
- imatinib + regorafenib Moderate
- isoniazid + regorafenib Moderate
Related conditions
Frequently asked questions
What drug class is regorafenib?
regorafenib belongs to: Oncology.
How does regorafenib work?
Tyrosine kinase inhibitor; shown to inhibit activity of membrane-bound and intracellular kinases involved in normal cellular functions and in pathological processes (eg, oncogenesis, tumor angiogenesis)
What are the common side effects of regorafenib?
Asthenia, Anemia, Increased AST, Lymphopenia, Proteinuria, Hypocalcemia, Hypophosphatemia
Which drugs interact with regorafenib?
carbamazepine, clarithromycin, enzalutamide, bosentan, chloramphenicol, dexamethasone, eslicarbazepine, imatinib, isoniazid
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