Drug reference
rifabutin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Anti TB)
Mechanism of action
Inhibits DNA-dependent RNA polymerase
Common side effects
- Rash
- Neutropenia
- Leukopenia
- Discoloration of urine
- Incr AST/ALT
Contraindications
- Contraindicated in patients who have had clinically significant hypersensitivity to rifabutin or to any other rifamycins.
Known interactions (4)
- apixaban + rifabutin Major
- clarithromycin + rifabutin Major
- cariprazine + rifabutin Moderate
- erythromycin + rifabutin Moderate
Related conditions
Frequently asked questions
What drug class is rifabutin?
rifabutin belongs to: Anti Bacterial.
How does rifabutin work?
Inhibits DNA-dependent RNA polymerase
What are the common side effects of rifabutin?
Rash, Neutropenia, Leukopenia, Discoloration of urine, Incr AST/ALT
Which drugs interact with rifabutin?
apixaban, clarithromycin, cariprazine, erythromycin
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.