Drug reference
rifampicin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Anti TB)
Mechanism of action
Inhibits DNA-dependent RNA polymerase by binding to beta subunit, which in turn blocks RNA transcription; potent enzyme inducer
Common side effects
- Rash
- Anorexia
- Vomiting
- Nausea
- Elevated liver function test (LFT)
- Epigastric distress
Contraindications
- Hypersensitivity to rifamycins or excipients Coadministration with atazanavir, darunavir, fosamprenavir, ritonavir/saquinavir, sazuinavir, lurasidone, or tipranavir
Related conditions
Frequently asked questions
What drug class is rifampicin?
rifampicin belongs to: Anti Bacterial.
How does rifampicin work?
Inhibits DNA-dependent RNA polymerase by binding to beta subunit, which in turn blocks RNA transcription; potent enzyme inducer
What are the common side effects of rifampicin?
Rash, Anorexia, Vomiting, Nausea, Elevated liver function test (LFT), Epigastric distress
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