Drug reference

saxagliptin-metformin

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Peptide analogues)

Mechanism of action

Saxagliptin: Dipeptidyl peptidase IV (DPP-4) inhibition that results in increased incretin hormones and enhanced glycemic control. Metformin: Biguanide; acts by decreasing endogenous hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

Common side effects

  • Constipation
  • Vomiting
  • Headache
  • Nausea
  • Hypoglycemia
  • Diarrhea

Related conditions

Frequently asked questions

What drug class is saxagliptin-metformin?

saxagliptin-metformin belongs to: Endocrine.

How does saxagliptin-metformin work?

Saxagliptin: Dipeptidyl peptidase IV (DPP-4) inhibition that results in increased incretin hormones and enhanced glycemic control. Metformin: Biguanide; acts by decreasing endogenous hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

What are the common side effects of saxagliptin-metformin?

Constipation, Vomiting, Headache, Nausea, Hypoglycemia, Diarrhea

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