Drug reference

streptokinase

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Cardiovascular (Fibrinolytics)

Mechanism of action

Streptokinase creates an active complex which promotes the cleavage of the Arg/Val bond in plasminogen to form the proteolytic enzyme plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action.

Common side effects

  • Bleeding
  • Gastrointestinal bleeding

Related conditions

Frequently asked questions

What drug class is streptokinase?

streptokinase belongs to: Cardiovascular.

How does streptokinase work?

Streptokinase creates an active complex which promotes the cleavage of the Arg/Val bond in plasminogen to form the proteolytic enzyme plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action.

What are the common side effects of streptokinase?

Bleeding, Gastrointestinal bleeding

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