Drug interactions
Agomelatine + Rifampicin
Severity: Moderate
Agomelatine and Rifampicin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rifampicin induces hepatic enzymes including CYP1A2 and may lower agomelatine plasma concentrations.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Agomelatine and Rifampicin interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Agomelatine
Other interactions of Rifampicin
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
