Drug interactions
Aliskiren + Ibuprofen
Severity: Moderate
Aliskiren and Ibuprofen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ibuprofen can reduce the antihypertensive effect of aliskiren and, in older, volume-depleted or renally impaired patients, may cause acute kidney injury.
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Other interactions of Ibuprofen
- Acemetacin + Ibuprofen Major
- Alteplase + Ibuprofen Major
- Amiloride + Ibuprofen Major
Other interactions of Aliskiren
- Aliskiren + Amlodipine-benazepril Contraindicated
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan Contraindicated
- Aliskiren + Amlodipine-olmesartan Contraindicated
Drug class
- Aliskiren
- Cardiovascular
- Ibuprofen
- Musculoskeletal
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