Drug interactions
Alteplase + Ibuprofen
Severity: Major
Alteplase and Ibuprofen: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alteplase causes thrombolysis and NSAIDs impair platelet function and damage gastric mucosa, so the combination raises the risk of serious bleeding.
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Other interactions of Ibuprofen
Other interactions of Alteplase
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