Drug interactions
Aliskiren + Itraconazole
Severity: Major
Aliskiren and Itraconazole: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Itraconazole substantially increases aliskiren exposure, which may cause hypotension and other adverse effects such as hyperkalemia or renal impairment, particularly in susceptible patients.
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Other interactions of Itraconazole
- Alfuzosin + Itraconazole Contraindicated
- Alprazolam + Itraconazole Contraindicated
Other interactions of Aliskiren
- Aliskiren + Amlodipine-benazepril Contraindicated
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan Contraindicated
- Aliskiren + Amlodipine-olmesartan Contraindicated
Drug class
- Aliskiren
- Cardiovascular
- Itraconazole
- Anti Fungals
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