Drug interactions
Almotriptan + Fluoxetine
Severity: Moderate
Almotriptan and Fluoxetine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combining an SSRI with a triptan carries a reported risk of serotonin syndrome, with agitation, tremor, hyperthermia, diarrhea and neuromuscular hyperactivity.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Almotriptan and Fluoxetine interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Almotriptan
- Almotriptan + Dihydroergotamine Contraindicated
- Almotriptan + Dihydroergotamine intranasal Contraindicated
- Almotriptan + Eletriptan Contraindicated
Drug class
- Almotriptan
- Central Nervous System
- Fluoxetine
- Central Nervous System
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
