Drug reference
fluoxetine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (SSRIs)
Mechanism of action
Selective serotonin reuptake inhibitor; little or no affinity for alpha-adrenergic histamine or cholinergic receptor
Common side effects
- Insomnia
- Anorexia
- Somnolence
- Headache
- Nausea
- Weakness
- Menstrual cycle disorientation.
- Diarrhea
Known interactions (17)
- fluoxetine + isocarboxazid Contraindicated
- fluoxetine + phenelzine Contraindicated
- fluoxetine + pimozide Contraindicated
- fluoxetine + selegiline Contraindicated
- fluoxetine + thioridazine Contraindicated
- fluoxetine + tranylcypromine Contraindicated
- fluoxetine + ibuprofen Major
- fluoxetine + linezolid Major
- fluoxetine + procarbazine Major
- fluoxetine + tramadol Major
- Alprazolam + fluoxetine Moderate
- fluoxetine + goserelin Moderate
- fluoxetine + leuprolide Moderate
- fluoxetine + Olanzapine Moderate
- fluoxetine + Ondansetron Moderate
- fluoxetine + Oxcarbazepine Moderate
- fluoxetine + Zolmitriptan Moderate
Related conditions
Frequently asked questions
What drug class is fluoxetine?
fluoxetine belongs to: Central Nervous System.
How does fluoxetine work?
Selective serotonin reuptake inhibitor; little or no affinity for alpha-adrenergic histamine or cholinergic receptor
What are the common side effects of fluoxetine?
Insomnia, Anorexia, Somnolence, Headache, Nausea, Weakness, Menstrual cycle disorientation., Diarrhea
Which drugs interact with fluoxetine?
isocarboxazid, phenelzine, pimozide, selegiline, thioridazine, tranylcypromine, ibuprofen, linezolid, procarbazine, tramadol, Alprazolam, goserelin, leuprolide, Olanzapine, Ondansetron
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