Drug interactions
Alogliptin-pioglitazone + Ketoconazole
Severity: Moderate
Alogliptin-pioglitazone and Ketoconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ketoconazole inhibits CYP enzymes and may raise pioglitazone concentrations, increasing the risk of dose-related effects such as edema and hypoglycemia.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Alogliptin-pioglitazone and Ketoconazole interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Alogliptin-pioglitazone
Other interactions of Ketoconazole
- Alfuzosin + Ketoconazole Contraindicated
- Alprazolam + Ketoconazole Contraindicated
Drug class
- Alogliptin-pioglitazone
- Endocrine
- Ketoconazole
- Anti Fungals
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.