Drug interactions
Alogliptin-pioglitazone + Tolbutamide
Severity: Moderate
Alogliptin-pioglitazone and Tolbutamide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tolbutamide is a sulfonylurea; combining it with alogliptin and pioglitazone increases glucose-lowering and the risk of hypoglycemia, which can be prolonged and severe in vulnerable patients.
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Other interactions of Alogliptin-pioglitazone
Other interactions of Tolbutamide
- Aceclofenac + Tolbutamide Moderate
- Acemetacin + Tolbutamide Moderate
- Acetylsalicylic acid + Tolbutamide Moderate
Drug class
- Alogliptin-pioglitazone
- Endocrine
- Tolbutamide
- Endocrine
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