Drug interactions
Alosetron + Topiramate
Severity: Minor
Alosetron and Topiramate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Topiramate may weakly induce CYP3A4, potentially lowering alosetron exposure, though alosetron is cleared by several CYP enzymes, mainly CYP2C9, 3A4 and 1A2.
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Other interactions of Alosetron
- Alosetron + Apomorphine Contraindicated
- Alosetron + Fluvoxamine Contraindicated
- Alosetron + Ciprofloxacin Major
Drug class
- Alosetron
- Gastrointestinal Tract
- Topiramate
- Central Nervous System
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