Drug interactions
Alpelisib + Bosentan
Severity: Moderate
Alpelisib and Bosentan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bosentan induces CYP3A4 and may reduce alpelisib exposure, though alpelisib is also cleared by non-CYP routes, so the effect is likely modest.
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Other interactions of Alpelisib
- Alpelisib + Carbamazepine Major
- Alpelisib + Phenytoin Major
- Alpelisib + Secobarbital Major
Drug class
- Alpelisib
- Oncology
- Bosentan
- Miscellaneous
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