Drug interactions
Alpelisib + Fluoxetine
Severity: Minor
Alpelisib and Fluoxetine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alpelisib may induce CYP2C9, and fluoxetine is partly metabolized by CYP2C9 along with CYP2D6, so fluoxetine exposure could fall modestly.
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Other interactions of Alpelisib
- Alpelisib + Carbamazepine Major
- Alpelisib + Phenytoin Major
- Alpelisib + Secobarbital Major
Drug class
- Alpelisib
- Oncology
- Fluoxetine
- Central Nervous System
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