Drug interactions
Alpelisib + Glyburide-metformin
Severity: Moderate
Alpelisib and Glyburide-metformin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alpelisib may induce CYP2C9 and so lower exposure to glyburide, reducing its glucose-lowering effect.
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Other interactions of Alpelisib
- Alpelisib + Carbamazepine Major
- Alpelisib + Phenytoin Major
- Alpelisib + Secobarbital Major
Drug class
- Alpelisib
- Oncology
- Glyburide-metformin
- Endocrine
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