Drug reference
glyburide-metformin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Endocrine (Insulin secretagogues)
Mechanism of action
Initial effect is to increase beta-cell insulin secretion May also decrease rate of hepatic glucose production, increase insulin receptor sensitivity, and increase number of insulin receptors
Common side effects
- Angioedema
- Vomiting
- Nausea
- Hypoglycemia
- Dermatologic reactions
- Heartburn
Known interactions (1)
- bosentan + glyburide-metformin Contraindicated
Related conditions
Frequently asked questions
What drug class is glyburide-metformin?
glyburide-metformin belongs to: Endocrine.
How does glyburide-metformin work?
Initial effect is to increase beta-cell insulin secretion May also decrease rate of hepatic glucose production, increase insulin receptor sensitivity, and increase number of insulin receptors
What are the common side effects of glyburide-metformin?
Angioedema, Vomiting, Nausea, Hypoglycemia, Dermatologic reactions, Heartburn
Which drugs interact with glyburide-metformin?
bosentan
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